Jo-Wilfried Tsonga has handed John Isner his second straight singles defeat at the Hopman Cup, beating the American 6-3, 6-2 to give France a 1-0 lead in the only tie between teams Tuesday.

Later Tuesday on hard court at the Perth Arena, Venus Williams faces Mathilde Johansson in an attempt to take the match into a decisive mixed doubles.

The Americans won their opening match at the eight-team tournament, beating South Africa on Sunday, while France lost to Spain.