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Originally published October 3, 2012 at 9:02 PM | Page modified October 3, 2012 at 9:28 PM

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Titans' Jake Locker out with shoulder injury, Matt Hasselbeck stepping in | NFL notebook

Jake Locker's left shoulder is sore enough that the Tennessee Titans don't even want him in uniform Sunday when they visit Minnesota, so...

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NASHVILLE, Tenn. — Jake Locker's left shoulder is sore enough that the Tennessee Titans don't even want him in uniform Sunday when they visit Minnesota, so veteran Matt Hasselbeck will start at quarterback.

Whether Locker, the former University of Washington star, misses more than one game depends on how quickly his non-throwing shoulder heals.

"We'll take it day by day," coach Mike Munchak said.

Locker dislocated his non-throwing shoulder for the second time in four games when he was sacked in last week's 38-14 loss at Houston.

Locker first hurt his shoulder in the season opener, with the shoulder popping out when he hit the turf on a sack. Locker said this injury feels different and he's not as comfortable as he was a month ago.

"It's just as fast as my body can respond to it," Locker said. "I'll do my best to get back there as soon as I can."

The Titans are 1-3.

"It's unfortunate anytime anybody gets hurt," Hasselbeck said. "I certainly feel bad for Jake and his injury. I've been there. I've had that injury. Nothing's fun. Sleeping's not fun. Nothing's fun. I feel badly for him."

Cardinals go for 5-0 in former home city

Thirty-eight years ago, the last time the Arizona Cardinals were 4-0, their home was St. Louis and they were known affectionately as the Big Red.

Nearly a quarter century since departing for the desert, they're on top of their game again.

The surprising Cardinals don't have one of the best offenses in the NFL, far from it actually. Throw out the big plays on defense and they're pretty much middle of the road there, too. Their games are going down to the wire, the last one ending in overtime and three of them decided by a total of nine points.

Not surprisingly, they're just a 1-point favorite to beat the St. Louis Rams. On Thursday night, the Cardinals will have a shot at being the first 2012 team to 5-0, two wins shy of the 7-0 start in 1974 by a team that featured Hall of Famers Dan Dierdorf, Roger Wehrli, Larry Wilson and Jackie Smith.

One of the advantages to all the close calls is there's no danger of overconfidence.

"Obviously, we're excited to be 4-0," coach Ken Whisenhunt said. "We've had four up-and-down games. We've had a lot of trauma in them, so there's been a lot of emotion extended.

"But just to be where we are, we're certainly pleased about that."

The Cardinals won the 500th game in club history last week after forcing overtime on Kevin Kolb's TD pass with 22 seconds to go.

Notes

• Things just got a lot tougher for the struggling New York Jets. Wide receiver Santonio Holmes will miss the rest of this season with an injured left foot, leaving the Jets without their top offensive playmaker. The team announced Wednesday that Holmes will need surgery. Holmes leads the Jets with 20 catches for 272 yards and a touchdown this season.

• Buffalo defensive tackle Kyle Williams is questioning why he's been fined $15,000 by the NFL for a roughing-the-passer penalty against Tom Brady. Williams was flagged after he was knocked to the turf and his arm caught the back of Brady's leg.

• Former NFL receiver Sam Hurd pleaded not guilty Wednesday to a new indictment accusing him of trying to obtain cocaine and marijuana while he was out on bond awaiting trial on charges of trying to start a drug ring in the Chicago area. The indictment filed last month is based on allegations that Hurd asked a cousin, Jesse Tyrone Chavful, to buy drugs.

• The Chiefs put tight end Kevin Boss on injured reserve with a head injury after doctors determined they would not clear him to play the rest of the year. Boss signed a $9 million, three-year deal in the offseason to provide a versatile tight end for quarterback Matt Cassel.

• The Jaguars have an NFL-low two sacks through four games and have failed to get an opposing quarterback to the ground the past three weeks.

• The NFL has granted permission for Saints coach Sean Payton, general manager Mickey Loomis and assistant head coach Joe Vitt to attend New Orleans' home game Sunday night against San Diego, in which Drew Brees can break a tie with Johnny Unitas for the NFL record of consecutive regular-season games with a touchdown pass (47).

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