WIMBLEDON, England — The shot that doomed Maria Sharapova on what was a manic middle Monday whizzed past at 108 mph, a first-rate second serve that crowned her third round-of-16 exit at Wimbledon in six years. But this loss was different for the Russian.

Never before had she roared into the All England Club ranked No. 1 in the world, as the top seed here, as the French Open champion — a triumph that completed her career Grand Slam. Sharapova, a Wimbledon finalist in 2011, was trounced Monday by No. 15 Sabine Lisicki of Germany, whose flat groundstrokes sent her scurrying from side to side and, ultimately, out of the tournament.

Lisicki lost her three previous matches against Sharapova, including in straight sets — by the same score, 6-4, 6-3 — in a Wimbledon semifinal last year.

Asked if she viewed this victory as revenge, Lisicki laughed and said, "Yeah, for all three of them, actually."

When second-seeded Victoria Azarenka of Belarus throttled Ana Ivanovic a few hours later, Sharapova's horrible day grew worse. Gone was her No. 1 world ranking, which she held for a month, and wanted desperately to retain.

Lisicki's quarterfinal opponent is countrywoman Angelique Kerber, who routed Belgian Kim Clijsters 6-1, 6-1 in 49 minutes.

American Serena Williams beat Yaroslava Shvedova of Kazakhstan 6-1, 2-6, 7-5 despite erratic baseline play.

"I feel like I can do a lot better, which is very comforting," Williams said. "Because if this is my best, I'm in trouble."

Some fourth-round men's matches were suspended because of rain.

No. 1 Novak Djokovic beat Viktor Troicki 6-3, 6-1, 6-3 in a matchup of players from Serbia and No. 3 Roger Federer of Switzerland beat Xavier Malisse of Belgium in four sets.

Note

• No. 4 Andy Murray of Scotland won the first set and was leading No. 16 Marin Cilic of Croatia 3-1 in the second when their match was suspended.