Stocks closed lower Wednesday following news that several top Federal Reserve officials are doubtful about continuing the central bank's economic stimulus. The S&P 500 index had its biggest loss of the year.

The Dow Jones industrial average fell 108.13 points, or 0.8 percent, to close at 13,927.54.

The S&P 500 index sank 18.99 points, or 1.2 percent, to 1,511.95.

The Nasdaq composite fell 49.19 points, or 1.5 percent, to 3,164.41.

For the week:

The Dow is down 54.22 points, or 0.4 percent.

The S&P 500 is down 7.84 points, or 0.5 percent.

The Nasdaq is down 27.62 points, or 0.9 percent.

For the year:

The Dow is up 823.40 points, or 6.3 percent.

The S&P 500 is up 85.76 points, or 6 percent.

The Nasdaq is up 144.90 points, or 4.8 percent